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R A Newman Selected Research

oleandrin

8/2001Inhibition of export of fibroblast growth factor-2 (FGF-2) from the prostate cancer cell lines PC3 and DU145 by Anvirzel and its cardiac glycoside component, oleandrin.
7/2000Cardiac glycosides stimulate Ca2+ increases and apoptosis in androgen-independent, metastatic human prostate adenocarcinoma cells.
7/2000Oleandrin suppresses activation of nuclear transcription factor-kappaB, activator protein-1, and c-Jun NH2-terminal kinase.
7/2000Anvirzel, an extract of Nerium oleander, induces cell death in human but not murine cancer cells.

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R A Newman Research Topics

Disease

14Neoplasms (Cancer)
12/2014 - 01/2000
4Prostatic Neoplasms (Prostate Cancer)
07/2010 - 07/2000
3Carcinogenesis
04/2008 - 07/2000
2Carcinoma (Carcinomatosis)
07/2010 - 09/2006
2Colonic Neoplasms (Colon Cancer)
04/2008 - 12/2000
2Colorectal Neoplasms (Colorectal Cancer)
12/2000 - 07/2000
1Diarrhea
12/2014
1Nausea
12/2014
1Fatigue
12/2014
1Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
07/2010
1Hyperplasia
07/2010
1Pancreatic Neoplasms (Pancreatic Cancer)
09/2008
1Lung Neoplasms (Lung Cancer)
10/2001
1Multiple Myeloma
07/2001
1Adenocarcinoma
07/2000
1Heart Diseases (Heart Disease)
07/2000
1Inflammation (Inflammations)
07/2000
1Mouth Neoplasms (Oral Cancer)
07/2000

Drug/Important Bio-Agent (IBA)

6Pharmaceutical PreparationsIBA
12/2014 - 01/2000
4oleandrinIBA
08/2001 - 07/2000
3Proteins (Proteins, Gene)FDA Link
07/2010 - 07/2000
2Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
12/2014 - 08/2001
2EnzymesIBA
07/2010 - 07/2000
2Arachidonic Acid (Vitamin F)IBA
07/2010 - 10/2001
2Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
10/2001 - 12/2000
2Paclitaxel (Taxol)FDA LinkGeneric
10/2001 - 01/2000
2Cardiac GlycosidesIBA
08/2001 - 07/2000
2AnvirzelIBA
08/2001 - 07/2000
2N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA
12/2000 - 07/2000
2Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
12/2000 - 07/2000
170-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
12/2014
1PBI-05204IBA
12/2014
1HeterochromatinIBA
07/2010
1Phenobarbital (Luminal)FDA Link
07/2010
1Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA
07/2010
1LipidsIBA
07/2010
1frondoside AIBA
09/2008
1GlycosidesIBA
09/2008
1TriterpenesIBA
09/2008
1CaspasesIBA
09/2008
1Alkylating AgentsIBA
04/2008
1PectinsIBA
04/2008
1Fish OilsIBA
04/2008
1PPAR gammaIBA
09/2006
1Dinoprostone (PGE2)FDA Link
10/2001
111-hydroxy-5,8,12,14-eicosatetraenoic acidIBA
10/2001
1Celecoxib (Celebrex)FDA Link
10/2001
1Epothilones (Epothilone)IBA
10/2001
126-fluoroepothilone BIBA
10/2001
1oleandrigeninIBA
08/2001
1Plant ExtractsIBA
08/2001
18-chloro-cyclic adenosine monophosphateIBA
07/2001
1TeaIBA
03/2001
1Mitomycin (Mitomycin-C)FDA LinkGeneric
02/2001
1sulindac sulfone (exisulind)IBA
12/2000
1AcidsIBA
12/2000
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
12/2000
1Sulindac (Copal)FDA LinkGeneric
07/2000
1AndrogensIBA
07/2000
1NF-kappa B (NF-kB)IBA
07/2000
1Digoxin (Digitek)FDA LinkGeneric
07/2000
1Ouabain (G Strophanthin)IBA
07/2000
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
07/2000
1ThapsigarginIBA
07/2000
1StaurosporineIBA
07/2000
1ChromatinIBA
07/2000
1Antineoplastic Agents (Antineoplastics)IBA
04/2000
1dolastatin 10IBA
04/2000
1cremophor ELIBA
01/2000
1paclitaxel poliglumex (XYOTAX)IBA
01/2000